Table 2 Clinical characteristics of patients across quartiles of AST/ALT ratio
Characteristic | Group 1 (≤ 0.91) | Group 2 (0.91–1.26) | Group 3 (1.26–1.73) | Group 4 (> 1.73) | p value |
|---|---|---|---|---|---|
N | 133 | 128 | 131 | 130 | |
Follow-up time (days) | 365 (53–365) | 365 (80.5–365) | 365 (67–365) | 224 (35–365) | 0.01 |
Sex, male | 58 (43.6) | 38 (29.7) | 44 (33.6) | 27 (20.8) | 0.001 |
Age, years | |||||
≤ 40 | 31 (23.3) | 20 (15.6) | 28 (21.4) | 22 (16.9) | 0.205 |
40–60 | 85 (63.9) | 85 (66.4) | 74 (56.5) | 78 (60) | |
> 60 | 17 (12.8) | 23 (18) | 29 (22.1) | 30 (23.1) | |
Diagnosis | |||||
DM | 82 (61.7) | 87 (68) | 86 (65.6) | 105 (80.8) | 0.046 |
CADM | 16 (12) | 12 (9.4) | 12 (9.2) | 7 (5.4) | |
PM | 35 (26.3) | 29 (22.7) | 33 (25.2) | 18 (13.8) | |
OLS | 11 (8.3) | 12 (9.4) | 16 (12.2) | 11 (8.5) | 0.681 |
Comorbidities | |||||
Diabetes mellitus | 8 (6) | 11 (8.6) | 8 (6.1) | 9 (6.9) | 0.834 |
Hypertension | 13 (9.8) | 20 (15.6) | 11 (8.4) | 10 (7.7) | 0.144 |
Chronic hepatitis B | 6 (4.5) | 3 (2.3) | 7 (5.3) | 8 (6.2) | 0.5 |
MDA5+ | 18 (13.5) | 17 (13.3) | 17 (13) | 18 (13.8) | 0.997 |
HB | 132 (122.5–144.5) | 123 (112–132) | 120 (111–131) | 116.5 (104.5–126) | < 0.001 |
PLT | 192 (140.5–233.5) | 194.5 (144–262) | 195 (154–261) | 196 (134.25–264.25) | 0.714 |
WBC | 8.07 (6.2–10.63) | 6.92 (4.68–10.52) | 5.89 (4.49–8.05) | 5.41 (3.97–7.81) | < 0.001 |
EO% | 0.3 (0–0.9) | 0.75 (0.3–2.58) | 1.6 (0.3–3.5) | 1 (0.18–2.83) | < 0.001 |
NLR | 4.28 (3.15–7.72) | 4.38 (3.02–6.84) | 4.03 (2.99–6.41) | 4.82 (2.88–7.93) | 0.278 |
ALB | 36.2 (33.55–39.05) | 34.75 (31.93–38.48) | 34.3 (30.9–38.3) | 32.15 (28.3–35.35) | < 0.001 |
UA/CREA | 5 (3.98–7.04) | 5.24 (4.36–6.58) | 5.35 (4.18–6.90) | 5.62 (4.32–7.30) | 0.476 |
TG | 1.92 (1.37–2.78) | 2.16 (1.56–2.79) | 1.77 (1.37–2.4) | 1.92 (1.44–2.79) | 0.032 |
LDL | 2.86 (2.3–3.52) | 2.44 (1.89–3.11) | 2.24 (1.64–2.77) | 1.86 (1.32–2.53) | < 0.001 |
CK | 69 (30.5–505.5) | 106.5 (41–1786.25) | 177 (67–1449) | 146.5 (59.75–992) | < 0.001 |
Cumulative proportion | |||||
No readmission | 0.967 | 0.908 | 0.890 | 0.814 | 0.002 |
No need for MV | 0.944 | 0.942 | 0.92 | 0.805 | 0.003 |
Survival rate | 0.927 | 0.898 | 0.881 | 0.733 | < 0.001 |