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Table 5 Anthropometric measurements and body composition changes during the study

From: Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study

 

Baseline (N = 107)

M1 (N = 106)

M3 (N = 104)

M6 (N = 97)

M12 (N = 77)

P*, M0 vs M6 (N = 97)

P*, M0 vs M12 (N = 77)

P#

Weight (kg)

70.3 ± 15.1

70.3 ± 14.8

71 ± 15.7

70.9 ± 15.3

72 ± 15.3

0.0037

0.0003

0.0005

Body mass index (kg/m2)

26.4 ± 5.5

26.4 ± 5.3

26.7 ± 5.7

26.7 ± 5.5

27.2 ± 5.8

0.0165

0.0006

0.0006

Waist circumference (cm)

90.3 ± 13.2

90.9 ± 15.5

93.4 ± 17

93.2 ± 14.7

93.9 ± 15.3

0.0008

0.006

0.0002

Waist-to-hip ratio

0.95 ± 0.06

0.95 ± 0.06

0.93 ± 0.06

0.95 ± 0.12

0.94 ± 0.1

0.94

0.77

0.9

Lean mass (kg)

40.76 ± 8.4

Not evaluated

Not evaluated

41.79 ± 8.8

42.11 ± 8.9

0.0097

0.021

0.028

Fat mass (kg)

27.7 ± 12.1

Not evaluated

Not evaluated

27.4 ± 10.7

28.15 ± 11.4

0.69

0.88

0.8

% fat

38.9 ± 10.3

Not evaluated

Not evaluated

38.7 ± 9.1

39.3 ± 9,8

0.59

0.56

0.6

Fat mass android region (kg)

2.52 ± 1.3

Not evaluated

Not evaluated

2.51 ± 1.3

2.67 ± 1.5

0.99

0.51

0.25

Fat mass gynoid region (kg)

4.5 ± 1.9

Not evaluated

Not evaluated

4.7 ± 2.7

4.6 ± 1.9

0.36

0.55

0.19

  1. Results are given as mean ± SD
  2. M month
  3. *Paired Student’s t test
  4. #Sensitivity analysis