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Table 5 Anthropometric measurements and body composition changes during the study

From: Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study

  Baseline (N = 107) M1 (N = 106) M3 (N = 104) M6 (N = 97) M12 (N = 77) P*, M0 vs M6 (N = 97) P*, M0 vs M12 (N = 77) P#
Weight (kg) 70.3 ± 15.1 70.3 ± 14.8 71 ± 15.7 70.9 ± 15.3 72 ± 15.3 0.0037 0.0003 0.0005
Body mass index (kg/m2) 26.4 ± 5.5 26.4 ± 5.3 26.7 ± 5.7 26.7 ± 5.5 27.2 ± 5.8 0.0165 0.0006 0.0006
Waist circumference (cm) 90.3 ± 13.2 90.9 ± 15.5 93.4 ± 17 93.2 ± 14.7 93.9 ± 15.3 0.0008 0.006 0.0002
Waist-to-hip ratio 0.95 ± 0.06 0.95 ± 0.06 0.93 ± 0.06 0.95 ± 0.12 0.94 ± 0.1 0.94 0.77 0.9
Lean mass (kg) 40.76 ± 8.4 Not evaluated Not evaluated 41.79 ± 8.8 42.11 ± 8.9 0.0097 0.021 0.028
Fat mass (kg) 27.7 ± 12.1 Not evaluated Not evaluated 27.4 ± 10.7 28.15 ± 11.4 0.69 0.88 0.8
% fat 38.9 ± 10.3 Not evaluated Not evaluated 38.7 ± 9.1 39.3 ± 9,8 0.59 0.56 0.6
Fat mass android region (kg) 2.52 ± 1.3 Not evaluated Not evaluated 2.51 ± 1.3 2.67 ± 1.5 0.99 0.51 0.25
Fat mass gynoid region (kg) 4.5 ± 1.9 Not evaluated Not evaluated 4.7 ± 2.7 4.6 ± 1.9 0.36 0.55 0.19
  1. Results are given as mean ± SD
  2. M month
  3. *Paired Student’s t test
  4. #Sensitivity analysis
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