Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study

Table 6 Relationships between changes in serum adipokines and changes in laboratory parameters of inflammation or disease activity at months 6 and 12 (R²: goodness-of-fit from linear regression)

R²	Time of assessment	ESR	CRP	IL-6	DAS28-ESR
Total adiponectin	M6	0.99	0.98	0.89	0.93
Total adiponectin	M12	0.78	0.75	0.88	0.64
HMW adiponectin	M6	0.92	0.93	0.99	0.76
HMW adiponectin	M12	0.67	0.64	0.94	0.42
Leptin	M6	0.37	0.46	0.09	0.53
Leptin	M12	0.81	0.81	0.36	0.94
leptin/fat mass	M6
leptin/fat mass	M12	0.91	0.45	0.96	0.91
Resistin	M6	0.19	0.11	0.51	0.08
Resistin	M12	0.26	0.31	0.27	0.51
Ghrelin	M6	0.32	0.31	0.74	0.01
Ghrelin	M12	0.09	0.04	0.23	0.07

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