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Table 2 Change from baseline in adapted SH and Poznanski scores

From: Tocilizumab may slow radiographic progression in patients with systemic or polyarticular-course juvenile idiopathic arthritis: post hoc radiographic analysis from two randomized controlled trials

Score Baseline Change from baseline to week 52 Change from baseline to week 104
n Median (IQR) n Median (IQR) P n Median (IQR) P
sJIA
 Adapted total SH 47 24.60 (8.50, 39.50) 45 0.00 (− 8.70, 4.00) 0.302 37 0.50 (− 7.50, 12.00) 0.695
 Erosion 47 8.50 (1.50, 23.50) 45 0.50 (− 3.50, 1.50) 0.677 37 0.50 (− 1.00, 4.50) 0.257
 JSN 47 13.00 (6.00, 19.50) 45 0.00 (− 4.00, 3.00) 0.257 37 0.00 (− 5.50, 4.00) 0.937
 Poznanski 33 − 2.38 (− 3.48, − 0.84) 32 0.29 (− 0.05, 1.05) 0.003 26 0.16 (− 0.01, 1.04) 0.057
pcJIA
 Adapted total SH 45 8.00 (3.00, 18.50) 40 0.50 (− 7.25, 4.50) 0.700 35 − 1.00 (− 6.50, 2.50) 0.109
 Erosion 45 3.00 (0.00, 6.50) 40 0.00 (− 1.50, 1.50) 0.819 36 0.00 (− 2.75, 0.75) 0.402
 JSN 45 5.00 (1.00, 14.50) 40 0.25 (− 5.25, 3.50) 0.614 35 − 1.00 (− 3.50, 1.50) 0.109
 Poznanski 35 − 1.45 (− 2.51, − 0.75) 31 0.26 (− 0.34, 0.91) 0.077 25 0.55 (0.04, 0.92) 0.004
  1. Abbreviations: IQR interquartile range, JSN joint space narrowing, pcJIA polyarticular-course juvenile idiopathic arthritis, SH Sharp–van der Heijde, sJIA systemic juvenile idiopathic arthritis
  2. SH score: higher score indicates greater damage. Poznanski score: the more negative a Poznanski score, the more severe the radiographic damage