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Table 1 Baseline demographic and clinical characteristics according to HAQ-DI score assessments

From: Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database

Parameters dcSSc with no HAQ-DI score at any time
N = 4132
dcSSc with ≥ 1 HAQ-DI score
N = 690
dcSSc with ≥ 2 HAQ-DI scores
N = 424
Age (years)
 Mean (SD) 52.2 (13.6) 53.8 (12.9) 53.1 (12.7)
 IQR 42.6–62.4 45.6–62.6 43.9–62.3
Age (years) at onset of RP, N 3953 677 414
 Mean (SD) 43.3 (14.7) 42.4 (14.4) 42.5 (14.3)
 IQR 32.7–54.0 32.4–52.0 32.1–52.3
Female, n (%) 3214 (77.8%) 537 (77.8%) 320 (75.5%)
Disease duration, n (%)
 ≤ 18 months 962 (23.3%) 60 (8.7%) 39 (9.2%)
 > 18 months 3170 (76.7%) 630 (91.3%) 385 (90.8%)
Current digital ulcers, n (%)
 Yes 1493 (36.6%) 120 (18.3%) 70 (17.3%)
 No 2585 (63.4%) 535 (81.7%) 335 (82.7%)
Puffy fingers, n (%)
 Yes 972 (48.7%) 216 (35.5%) 148 (39.1%)
 No 1024 (51.3%) 392 (64.5%) 231 (60.9%)
mRSS, N 3895 656 403
 Mean (SD) 16.4 (9.9) 11.7 (9.0) 11.8 (8.6)
 IQR 9.0–23.0 5.0–17.0 5.0–17.0
HAQ-DI score
 Mean (SD) NA 1.0 (0.8) 1.1 (0.8)
 IQR NA 0.4–1.6 0.4–1.8
Advanced organ involvement, n (%)
 None 3448 (83.7%) 468 (68.8%) 295 (69.9%)
 One 585 (14.2%) 178 (26.2%) 108 (25.6%)
 Multiple 86 (2.1%) 34 (5.0%) 19 (4.5%)
 Missing 13 10 2
  1. dcSSc diffuse cutaneous systemic sclerosis, HAQ-DI Health Assessment Questionnaire-Disability Index, IQR interquartile range, mRSS Modified Rodnan Skin Score, NA not available, RP Raynaud’s phenomenon, SD standard deviation