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Table 3 Multivariable Cox regression analysis of factors affecting risk of death in patients with ≥ 1 HAQ-DI measurement

From: Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database

Baseline parameter HR 95% CI for HR p value
HAQ-DI score 2.69 1.71, 4.23 < 0.001
Age at onset of RP 1.02 0.99, 1.04 0.177
mRSS 1.01 0.98, 1.04 0.527
Male gender 1.06 0.48, 2.35 0.888
Immunomodulator treatment 0.41 0.20, 0.84 0.014
Corticosteroids > 10 mg/day 5.41 2.10, 13.97 < 0.001
Advanced organ involvement (reference: no organ involvement)
 One 3.57 1.77, 7.18 < 0.001
 Multiple 4.81 1.73, 13.34 0.003
  1. CI confidence interval, HAQ-DI Health Assessment Questionnaire-Disability Index, HR hazard ratio, mRSS Modified Rodnan Skin Score, RP Raynaud’s phenomenon