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Table 3 Multivariable Cox regression analysis of factors affecting risk of death in patients with ≥ 1 HAQ-DI measurement

From: Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database

Baseline parameter

HR

95% CI for HR

p value

HAQ-DI score

2.69

1.71, 4.23

< 0.001

Age at onset of RP

1.02

0.99, 1.04

0.177

mRSS

1.01

0.98, 1.04

0.527

Male gender

1.06

0.48, 2.35

0.888

Immunomodulator treatment

0.41

0.20, 0.84

0.014

Corticosteroids > 10 mg/day

5.41

2.10, 13.97

< 0.001

Advanced organ involvement (reference: no organ involvement)

 One

3.57

1.77, 7.18

< 0.001

 Multiple

4.81

1.73, 13.34

0.003

  1. CI confidence interval, HAQ-DI Health Assessment Questionnaire-Disability Index, HR hazard ratio, mRSS Modified Rodnan Skin Score, RP Raynaud’s phenomenon