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Table 4 Multivariable linear regression analysis of effect of baseline characteristics on HAQ-DI score progression at 1 year

From: Health Assessment Questionnaire-Disability Index (HAQ-DI) use in modelling disease progression in diffuse cutaneous systemic sclerosis: an analysis from the EUSTAR database

  B 95% CI for B p value
Constant − 0.16 − 0.51, 0.20 0.389
HAQ-DI score at baseline − 0.15 − 0.27, − 0.04 0.009
Age at onset of RP − 0.002 − 0.01, 0.004 0.518
Male gender 0.02 − 0.18, 0.22 0.834
mRSS 0.01 0.0001, 0.03 0.048
Immunomodulator treatment 0.02 − 0.17, 0.20 0.870
Corticosteroids > 10 mg/day 0.12 − 0.77, 1.01 0.791
Advanced organ involvementa − 0.15 − 0.67, 0.37 0.575
Advanced lung involvement 0.05 − 0.55, 0.65 0.866
Advanced cardiac involvement 0.62 − 0.36, 1.60 0.213
Advanced GI involvementb 0.40 − 0.20, 0.99 0.186
Advanced renal involvement 0.47 − 0.56, 1.50 0.367
Esophageal symptoms 0.33 0.14, 0.52 0.001
Stomach symptoms − 0.04 − 0.25, 0.16 0.670
Intestinal symptoms 0.09 − 0.09, 0.26 0.335
  1. CI confidence interval, GI gastrointestinal, HAQ-DI Health Assessment Questionnaire-Disability Index, mRSS modified Rodnan Skin Score, RP Raynaud’s phenomenon
  2. aInvolved organs coded as 0 = none, 1 = one organ involvement, 2 = multiple organ involvement
  3. bMalabsorption or ≥ 10% weight loss from baseline