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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency

Fig. 2

Anti-cyclic citrullinated peptide (CCP) antibody and anti-cyclic arginine peptide (CAP) antibody titers. a Comparison of citrullination dependency between rheumatoid arthritis (RA)-overlapping connective tissue diseases (CTD) and non-RA CTD patients. The reactivities to CAP and CCP of sera from RA-overlapping CTD patients and non-RA CTD patients were measured by an in-house ELISA and absorbance values at 415 nm, and the absorbance values of anti-CAP antibodies were subtracted from those of anti-CCP antibodies for each patient. b A similar analysis was performed by stratifying all samples for which HLA data were available based on positivity for the HLA-DR shared epitope (SE). Horizontal dashed lines in a and b represent the cut-off level (= 0.1) of citrullination dependency

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Arthritis Research & Therapy

ISSN: 1478-6362

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