Variable | Group 1 (n = 680) | Group 2 (n = 388) | Group 3 (n = 457) | Group 4 (n = 500) | Group 5 (n = 229) | Group 6 (n = 288) | Total (n = 2542) |
---|---|---|---|---|---|---|---|
Age, years | 68.1 (5.1) | 67.8 (5.0) | 68.8 (5.2) | 69.9 (5.2) | 68.2 (5.2) | 69.4 (5.08) | 68.7 (5.2) |
Female, n, % | 439, 64.6 | 136, 35.1 | 253, 55.4 | 421, 84.2 | 176, 76.9 | 200, 69.4 | 1625, 63.9 |
BMI, kg/m2 | 20.5 (2.1) | 22.9 (2.3) | 22.7 (2.3) | 21.5 (2.0) | 21.7 (3.2) | 27.4 (2.6) | 22.4 (3.1) |
Radiographic severity, n, % | |||||||
K/L grade 0 | 61, 9.0 | 13, 3.4 | 21, 4.6 | 0, 0 | 8, 3.5 | 0, 0 | 103, 4.1 |
K/L grade 1 | 619, 91.0 | 291, 75.0 | 369, 80.7 | 0, 0 | 140, 61.1 | 46, 16.0 | 1465, 57.6 |
K/L grade 2 | 0, 0 | 76, 19.6 | 63, 13.8 | 371, 74.2 | 62, 27.1 | 163, 56.6 | 735, 28.9 |
K/L grade 3 | 0, 0 | 8, 2.1 | 4, 0.9 | 114, 22.8 | 18, 7.9 | 72, 25.0 | 216, 8.5 |
K/L grade 4 | 0, 0 | 0, 0 | 0, 0 | 15, 3.0 | 1, 0.4 | 7, 2.4 | 23, 0.9 |
MHI-5 score | 71 (8.1) | 73 (7.9) | 71 (8.4) | 71 (8.3) | 44 (7.5) | 72 (8.6) | 69 (11.3) |
Depressive symptoms, n, % | 0, 0 | 0, 0 | 0, 0 | 0, 0 | 229, 100 | 0, 0 | 229, 9.0 |
hs-CRP mean (SD), median, μg/ml | 0.26 (0.16), 0.22 | 0.77 (1.17), 0.48 | 2.43 (3.71), 1.14 | 0.38 (0.35), 0.27 | 0.93 (3.05), 0.38 | 1.14 (1.52), 0.66 | 0.91 (2.1), 0.41 |
BMD (T score) | − 1.6 (0.63) | 0.21 (0.76) | − 1.7 (0.62) | − 1.7 (0.68) | − 1.4 (0.89) | − 1.2 (0.72) | − 1.3 (0.95) |