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Table 4 Characteristics of subgroups

From: Obesity with radiological changes or depression was associated with worse knee outcome in general population: a cluster analysis in the Nagahama study

Variable

Group 1 (n = 680)

Group 2 (n = 388)

Group 3 (n = 457)

Group 4 (n = 500)

Group 5 (n = 229)

Group 6 (n = 288)

Total (n = 2542)

Age, years

68.1 (5.1)

67.8 (5.0)

68.8 (5.2)

69.9 (5.2)

68.2 (5.2)

69.4 (5.08)

68.7 (5.2)

Female, n, %

439, 64.6

136, 35.1

253, 55.4

421, 84.2

176, 76.9

200, 69.4

1625, 63.9

BMI, kg/m2

20.5 (2.1)

22.9 (2.3)

22.7 (2.3)

21.5 (2.0)

21.7 (3.2)

27.4 (2.6)

22.4 (3.1)

Radiographic severity, n, %

 K/L grade 0

61, 9.0

13, 3.4

21, 4.6

0, 0

8, 3.5

0, 0

103, 4.1

 K/L grade 1

619, 91.0

291, 75.0

369, 80.7

0, 0

140, 61.1

46, 16.0

1465, 57.6

 K/L grade 2

0, 0

76, 19.6

63, 13.8

371, 74.2

62, 27.1

163, 56.6

735, 28.9

 K/L grade 3

0, 0

8, 2.1

4, 0.9

114, 22.8

18, 7.9

72, 25.0

216, 8.5

 K/L grade 4

0, 0

0, 0

0, 0

15, 3.0

1, 0.4

7, 2.4

23, 0.9

MHI-5 score

71 (8.1)

73 (7.9)

71 (8.4)

71 (8.3)

44 (7.5)

72 (8.6)

69 (11.3)

 Depressive symptoms, n, %

0, 0

0, 0

0, 0

0, 0

229, 100

0, 0

229, 9.0

hs-CRP mean (SD), median, μg/ml

0.26 (0.16), 0.22

0.77 (1.17), 0.48

2.43 (3.71), 1.14

0.38 (0.35), 0.27

0.93 (3.05), 0.38

1.14 (1.52), 0.66

0.91 (2.1), 0.41

BMD (T score)

− 1.6 (0.63)

0.21 (0.76)

− 1.7 (0.62)

− 1.7 (0.68)

− 1.4 (0.89)

− 1.2 (0.72)

− 1.3 (0.95)

  1. Values are mean (SD), except where otherwise indicated
  2. Percentages may not sum to 100 because of rounding
  3. Scores on the MHI-5 range from 0 to 100, with higher scores indicating better mental health. MHI-5 ≤ 52 were considered as having depressive symptoms
  4. Defined groups are 1 = “minimal joint disease subgroup,” 2 = “male and high BMD subgroup,” 3 = “high CRP subgroup,” 4 = “severe ROA subgroup,” 5 = “depressive subgroup,” and 6 = “moderate ROA with high BMI subgroup”
  5. BMD bone mineral density, BMI body mass index, hs-CRP high-sensitivity C-reactive protein, K/L Kellgren/Lawrence, MHI-5 Mental Health Inventory-5, ROA radiographic knee OA