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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: MicroRNA-320a: an important regulator in the fibrotic process in interstitial lung disease of systemic sclerosis

Fig. 3

Expression of collagen genes were altered following overexpression and knockdown of miR-320a. Normal human pulmonary fibroblasts were transfected with miR-320a mimics, miR-320a inhibitors, and scramble as control. a mRNA levels for COL1A1 decreased after miR-320a overexpression as compared with the control group while the levels increased after knockdown of miR-320a. b mRNA levels for COL3A1 decreased after miR-320a overexpression as compared with the control group while the levels increased after knockdown of miR-320a. Experiments were repeated at least 3 times. Values are means ± SD. **p < 0.01 versus scramble controls. ***p < 0.001 versus scramble controls

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Arthritis Research & Therapy

ISSN: 1478-6362

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