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Table 2 B cell phenotype definitions

From: Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients

B cell type

Population phenotype

JBCs

CD19+ Jo-1-GST+

Non-JBCs

CD19+ Jo-1-GST−

BND

CD19+ CD27− IgD+ IgMlo/−

CD21lo

CD19+ CD21lo/−

CD21lo CD27+ memory

CD21lo CD27+ IgD−

Unswitched memory

CD19+ CD27+ IgD+ IgM+

Switched memory

CD19+ CD27+ IgD− IgM− IgG+

IgM memory

CD19+ CD27+ IgD− IgM+

Atypical memory

CD19+ CD24− CD27− CD38− IgD−

Transitional

CD19+ CD10+ CD24hi CD27− CD38+ IgD+

Plasmablasts

CD19+ CD24− CD38hi

  1. All populations were additionally gated on live, singlet lymphocytes