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Table 1 Characteristics of the study group

From: Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis

 

Active LN (n = 16)

Stable LN (n = 10)

AAV (n = 6)

IgAN (n = 9)

MCD/FSGS (MCD, n = 4; FSGS, n = 1)

HC (n = 8)

Age (years)

31 (23–45)

53 (31.75–61.25)

52 (45.5–59.5)

45 (35.5–57)

53 (40.5–62)

49.5 (40.5–55.5)

Female, n (%)

15 (93.75)

10 (100)

4 (66.67)

8 (88.89)

3 (60)

6 (75)

WBC count,  × 103/mL

4.43 (3.32–6.54)

4.30 (3.67–4.89)

9.98 (6.89–15.37)

8.1 (7.36–8.35)

8.02 (6.28–10.01)

5.44 (4.56–7.77)

CRP, mg/L

0.15 (0.07–1.15)

0.05 (0.03–0.16)

2.21 (0.38–10.35)

0.03 (0.01–0.15)

0.04 (0.02–0.05)

0.02 (0.01–0.05)

Serum BUN, mg/dL

14.5 (12–18.75)

15.5 (12.25–22.25)

31 (21.75–58.75)

17 (14.5–27)

14 (11.5–23.5)

15 (11–16)

UPCR, mg/mg

2.93 (0.90–5.87)

0.21 (0.09–0.36)

2.16 (1.233–2.97)

1.6 (0.90–4.62)

9.55 (3.99–16.88)

0.05 (0.04–0.11)

Serum anti-dsDNA, IU/ml

512 (267.9–849.8)

6.7 (2–155.9)

N/A

N/A

N/A

N/A

C3, mg/dL

44.5 (39.5–59.75)

69.5 (47.75–84.75)

106.5 (93.75–112.3)

99 (85–124)

N/A

N/A

C4, mg/dL

8 (5.5–16)

10.5 (4.5–21)

25 (12.5–30.25)

28 (20.5–32.5)

N/A

N/A

  1. The data are presented as the median and interquartile range (IQR) or as number (percentage)
  2. Abbreviations: LN lupus nephritis, AAV ANCA-associated vasculitis, IgAN IgA nephropathy, MCD minimal change disease, FSGS focal segmental glomerulosclerosis, HC healthy control, WBC white blood cell, CRP C-reactive protein, BUN blood urea nitrogen, UPCR urine protein to creatinine ratio, dsDNA double-stranded DNA, C3 complement component 3, C4 complement component 4