Fig. 5
From: MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1
Toluidine blue staining results of MCCs transfected with miR-21-5p mimic (a) or miR-21-5p inhibitor (c), followed by stimulation with IL-1β for 24 h. Scale bar, 50 μm (magnification, × 200). Lower panel, statistical analysis of the average optical density of matrix staining by toluidine blue. Asterisk (*): compared with the mimic NC (b) or inhibitor NC group (d). Hash (#): compared with the mimic NC + IL-1β or inhibitor NC + IL-1β group. Data are represented as the means ± standard deviation (n = 3). *P < 0.05, #P < 0.05. NS, not significant. Scale bar, 50 μm