Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative

Table 3 Cross-sectional associations between site-specific BML score and pain on climbing stairs, on walking, and on standing

Site-specific BML scores	Pain on climbing		Pain on walking		Pain on standing
Site-specific BML scores	Β (95% CI)	p	Β (95% CI)	p	Β (95% CI)	p
Medial FT joint	0.06(−0.02–0.14)	0.13	0.11(0.02–0.20)	0.01*	0.10 (0.04–0.20)	0.04*
Lateral FT joint	0.01(−0.18–0.20)	0.91	− 0.15 (− 0.40–0.11)	0.26	− 0.01 (− 0.26–0.23)	0.93
Medial PF joint	0.13(− 0.004–0.26)	0.06	− 0.07 (− 0.24–0.11)	0.45	− 0.05 (− 0.22–0.13)	0.62
Lateral PF joint	0.14 (0.02–0.25)	0.02*	0.08 (− 0.06–0.22)	0.28	0.12 (− 0.03–0.26)	0.10
Subspinous region	0.03(−0.18–0.23)	0.80	− 0.10 (− 0.35–0.16)	0.46	− 0.20 (− 0.48–0.07)	0.13

B: BML subscores adjusted for BML at the other four joint compartments, non-weight-bearing pain, age, sex, BMI, the other OA-related MRI features and anterior cruciate ligament tears.*p < 0.05
BML bone marrow lesion, FT femorotibial, PF patellofemoral

ISSN: 1478-6362