Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative

Table 4 Cross-sectional associations between OA-related MRI features and non-weight-bearing pain

	Spearmans’ r	p	Β₁ (95% CI)	p	Β₂ (95% CI)	p
Total BML score	0.19	< 0.001**	− 0.01 (− 0.06–0.04)	0.63	− 0.04 (− 0.10–0.02)	0.21
Articular cartilage score	0.22	< 0.001**	0.01 (− 0.02–0.04)	0.45	− 0.01 (− 0.06–0.04)	0.65
Osteophytes score	0.20	< 0.001**	0.02 (− 0.01–0.05)	0.15	0.02 (− 0.01–0.05)	0.15
Hoffa’s synovitis score	0.11	< 0.001**	0.08 (− 0.16–0.32)	0.52	0.06 (− 0.20–0.31)	0.68
Effusion score	0.18	< 0.001**	− 0.02 (− 0.18–0.18)	0.99	− 0.01 (− 0.004–0.36)	0.90
Medial meniscus extrusion score	0.20	< 0.001*	0.16 (0.01–0.32)	0.04*	0.18 (− 0.55–0.68)	0.045*

B₁: OA-related MRI features adjusted for weight-bearing pain, age, sex and BMI. B₂: OA-related MRI features adjusted for weight-bearing pain, age, sex, BMI, the other OA-related MRI features, and anterior cruciate ligament tears. *p < 0.05, ** p < 0.01
BML bone marrow lesion, FT femorotibial, PF patellofemoral

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