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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis

Fig. 1

Combination of CUR and VO-enriched diet reduced disease severity and suppressed clinical scores in CIA mice. Saline control and CIA mice under different conditions as indicated were monitored for disease severity and assigned clinical scores from day 21 after the first CII challenge. a Line graphs representing the mean clinical scores of mice fed with normal diet and VO-enriched diet, starting from day 1 to day 29. b Box plots representing the clinical scores on day 29, and percent clinical scores compared to CIA mice on the normal diet. GraphPad Prism 7.05 software was used for statistical analyses. Kruskal–Wallis one-way ANOVA followed by Dunn’s multiple comparison post hoc test was used to determine the p values (*p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001)

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