Table 1 Clinical and pathological characteristics of the patients
Characteristics | Value |
|---|---|
Age, median (IQR) | 56.0 (50.3, 64.0) |
Gender, male, n (%) | 44 (61.1) |
Serum IgG4 (mg/dl), median (IQR) | 770.0 (230.8, 1870.0) |
IgG4-RD RI | 4.0 (2.0, 6.3) |
Serum IgG4, n (%) | |
< 1 ULN | 14 (19.4) |
1 ~ 2 ULN | 11 (15.3) |
2 ~ 5 ULN | 14 (19.4) |
≥ 5 ULN | 32 (44.4) |
Missing value | 1 (1.4) |
Biopsy method, n (%) | |
Needle biopsy | 24 (33.3) |
Surgical biopsy | 48 (66.7) |
Biopsy organ, n (%) | |
Meninges | 1 (1.4) |
Lacrimal gland | 6 (8.3) |
Salivary gland | 41 (56.9) |
Lymph node | 8 (11.1) |
Lung | 2 (2.8) |
Pleura | 1 (1.4) |
Pancreas | 2 (2.8) |
Bile duct | 1 (1.4) |
Retroperitoneum | 9 (12.5) |
Prostate | 1 (1.4) |
IgG4/HPF, median (IQR) | 80.0 (50.0, 130.0) |
IgG4/HPF, n (%) | |
> 10 | 66 (91.7) |
≤ 10 | 3 (4.2) |
Indetermined | 3 (4.2) |
IgG4/IgG (%), mean ± SD | 67.5 ± 23.3 |
IgG4/IgG, n (%) | |
> 40% | 62 (86.1) |
≤ 40% | 9 (12.5) |
Indetermined | 1 (1.4) |
Lymphoplasmacytic infiltrate | 72 (100.0) |
Storiform fibrosis, n (%) | 35 (48.6) |
Obliterative phlebitis, n (%) | 23 (31.9) |
2019 ACR/EULAR Criteria Score, median (IQR) | 39.5 (31.3, 47.3) |
2011 comprehensive diagnostic criteria, n (%) | |
Possible | 11 (15.3) |
Probable | 14 (19.4) |
Definite | 47 (65.3) |
2011 Pathology diagnostic consensus, n (%) | |
Insufficient | 30 (41.7) |
Probable | 18 (25.0) |
Highly suggestive | 24 (33.3%) |