Skip to main content

Table 1 Baseline characteristics of patients in the included studies

From: Risk factors for mortality of diffuse alveolar hemorrhage in systemic lupus erythematosus: a systematic review and meta-analysis

No. Author, year Country Study population Study type Time span Number of patients (gender) Prognostic factors Mortality rate (%) NOS score
1 Zamora, 1997 USA SLE patients from a single cohort Retrospective cohort study 1984–1994 15 (10 females, 5 male) CTX treatment, mechanical ventilator, infection 42.1 8
2 Chang, 2002 China SLE patients from a single cohort Retrospective cohort study 1994–2001 8 (all females) APACHE II score, OSF score 50.0 8
3 Badsha, 2004 Singapore SLE patients from a single cohort Retrospective cohort study 1994–2001 22 (20 females, 2 males) SLEDAI, SLAM 36.4 8
4 Kwok, 2011 South Korea SLE patients from a single cohort Retrospective cohort study 1993–2009 21 (19 females, 2 males) Mechanical ventilator, infection 61.9 9
5 Martínez-Martínez, 2014 Mexico SLE patients from 9 cohorts Retrospective cohort study NA 50 patients with 57 episodes (49 females, 8 males) Creatinine, platelets, APACHE II score, mechanical ventilator, infection 42.1 8
6 Kim, 2017 South Korea SLE patients from a single cohort Retrospective cohort study 2004–2014 24 (all females) Lupus nephritis, plasmapheresis, transfusion, mechanical ventilator 29.2 9
7 Quintana, 2019 Colombia SLE patients from a single cohort Retrospective cohort study 2011–2018 17 (11 females, 6males) Disease duration, albumin, SLEDAI, inotropic/vasoactive use, mechanical ventilator 29.4 7
8 Sun, 2020 China SLE patients from a single cohort Retrospective cohort study 2004–2019 94 (82 females, 12 males) Lupus nephritis, platelets, CTX treatment, mechanical ventilator 38.3 9
  1. NOS Newcastle-Ottawa Scale, SLE systemic lupus erythematosus, CTX cyclophosphamide, APACHE II Acute Physiology, Age, and Chronic Health Evaluation, OSF organ system failure, SLEDAI systemic lupus erythematosus activity index, SLAM systemic lupus activity measure, NA not available