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Table 2 Changes in organ damage before and after the introduction of MPZ

From: Effectiveness and safety of mepolizumab in combination with corticosteroids in patients with eosinophilic granulomatosis with polyangiitis

 

Pre-MPZ

Post-MPZ

-12 M

-11 M

-9 M

-6 M

0 M

1 M

3 M

6 M

12 M

General symptoms

0

0

1 (6.3%)

1 (6.3%)

1 (6.3%)

1 (6.3%)

0

1 (6.3%)

0

Cutaneous manifestations

1 (6.3%)

1 (6.3%)

1 (6.3%)

1 (6.3%)

2 (12.5%)

2 (12.5%)

0

1 (6.3%)

0

ENT manifestations

6 (37.5%)

6 (37.5%)

6 (37.5%)

6 (37.5%)

6 (37.5%)

6 (37.5%)

6 (37.5%)

4 (25.0%)

3 (18.8%)

Chest manifestations

6 (37.5%)

6 (37.5%)

8 (50.0%)

8 (50.0%)

11 (68.8%)

5 (31.3%)

2 (12.5%)

2 (12.5%)

2 (12.5%)

Nervous system manifestations

7 (45.8%)

7 (45.8%)

7 (45.8%)

8 (50.0%)

8 (50.0%)

8 (50.0%)

7 (43.8%)

7 (43.8%)

7 (43.8%)

  1. ENT ear, nose, throat