|
Analyte
|
12 Week
|
24 Week
|
40 Week
|
|---|
|
Chow, n = 6
|
HF, n = 6
|
Western, n = 6
|
p value
|
Chow, n = 5
|
HF, n = 6
|
Western, n = 6
|
p value
|
Chow, n = 5
|
HF, n = 6
|
Western, n = 6
|
p value
|
|---|
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
|---|
|
IL-1B
|
13.9 (17.5)
|
32.3 (58.6)
|
39.4 (43.8)
|
0.54
|
22.5 (26.9)
|
15.3 (15.7)
|
41.1 (89.3)
|
0.72
|
2.0 (1.8)
|
2.0 (1.4)
|
6.4 (6.7)
|
0.16
|
|
IL-6
|
17.2 (14.3)
|
20.9 (28.1)
|
47.6 (67.0)
|
0.43
|
25.7 (31.9)
|
28.7 (35.0)
|
13.6 (12.2)
|
0.63
|
2.7 (3.8)
|
4.1 (1.9)
|
20.0 (30.2)
|
0.24
|
|
IL-10
|
45.8 (51.4)
|
56.6 (85.1)
|
153 (261.2)
|
0.47
|
19.0 (24.1)
|
17.2 (18.7)
|
15.1 (18.7)
|
0.95
|
0.5 (1.0)
|
0.4 (0.9)
|
2.1 (2.9)
|
0.25
|
|
IP-10
|
129.4 (53.8)
|
122.0 (32.4)
|
139.5 (38.7)
|
0.78
|
90.9 (53.2)
|
105.9 (43.8)
|
63.6 (49.5)
|
0.34
|
106 (14.3)
|
113.7 (24.2)
|
144.7 (67.9)
|
0.32
|
|
KC
|
453.4 (323.3)
|
690.2 (843.0)
|
856.0 (1324)
|
0.75
|
527.2 (363.1)
|
452.0 (230.1)
|
240.7 (108.5)
|
0.17
|
191.1 (85.0)
|
355.3 (223.4)
|
258.8 (139.5)
|
0.28
|
|
MCP-1
|
53.7 (58.7)
|
51.6 (46.4)
|
78.3 (65.6)
|
0.68
|
54.3 (23.8)
|
68.1 (42.3)
|
165.2 (259.5)
|
0.45
|
13.6 (9.6)
|
63.8 (39.1)
|
135.3 (93.7) *#
|
0.02*
|
|
TNFa
|
28.4 (31.4)
|
37.8 (54.2)
|
41.9 (35.0)
|
0.85
|
23.9 (23.6)
|
16.0 (22.7)
|
53.4 (96.2)
|
0.54
|
1.0 (1.9)
|
2.2 (4.1)
|
3.0 (5.1)
|
0.63
|
|
VEGF
|
2.2 (1.87)
|
6.8 (14.2)
|
13.1 (27.8)
|
0.59
|
2.9 (4.2)
|
1.5 (2.5)
|
1.9 (2.1)
|
0.73
|
5.4 (8.4)
|
2.1 (3.1)
|
1.0 (0.5)
|
0.33
|
- Values are displayed in pg/mL and analyzed by one-way ANOVA. P < 0.05 is significant
- *Significantly different from chow diet by Tukey's post hoc test
- #Significantly different from HF diet by Tukey’s post hoc test
