Table 1 Mean score difference in PROs associated with a one-point difference in PASDAS or ScoreMDA
PRO* | Mean score difference (95% CI) in PROs associated with a one-point difference | |
|---|---|---|
PASDAS | ScoreMDA | |
EQ-5D-3L VAS, mm | ||
 OPAL Broaden | −6.7 (− 7.2, − 6.3) | 5.0 (4.6, 5.4) |
 OPAL Beyond | − 6.9 (− 7.5, − 6.4) | 5.5 (4.9, 6.1) |
EQ-5D-3L UI | ||
 OPAL Broaden | − 0.1 (− 0.1, − 0.1) | 0.0 (0.0, 0.1) |
 OPAL Beyond | −0.1 (− 0.1, − 0.1) | 0.1 (0.1, 0.1) |
FACIT-F total score | ||
 OPAL Broaden | −2.8 (− 3.0, − 2.6) | 1.9 (1.8, 2.1) |
 OPAL Beyond | −3.3 (− 3.6, − 3.1) | 2.7 (2.5, 3.0) |
FACIT-F ED | ||
 OPAL Broaden | −1.3 (− 1.4, − 1.2) | 0.9 (0.8, 0.9) |
 OPAL Beyond | −1.4 (− 1.6, − 1.3) | 1.2 (1.1, 1.3) |
FACIT-F ID | ||
 OPAL Broaden | −1.6 (− 1.7, − 1.4) | 1.1 (1.0, 1.2) |
 OPAL Beyond | −1.9 (− 2.0, − 1.7) | 1.5 (1.4, 1.7) |
PGJS-VAS, mm | ||
 OPAL Broaden | 12.0 (11.6, 12.4) | −7.6 (− 8.0, − 7.2) |
 OPAL Beyond | 12.6 (12.1, 13.1) | − 9.2 (− 9.9, − 8.6) |
PGJS-VAS-PsO, mm | ||
 OPAL Broaden | 9.9 (9.4, 10.5) | −6.0 (− 6.5, − 5.6) |
 OPAL Beyond | 10.4 (9.7, 11.1) | − 7.2 (− 8.0, − 6.5) |
SF-36v2 PCS | ||
 OPAL Broaden | NA | 2.0 (1.9, 2.2) |
 OPAL Beyond | NA | 2.5 (2.3, 2.7) |
SF-36v2 PF | ||
 OPAL Broaden | NA | 2.1 (2.0, 2.3) |
 OPAL Beyond | NA | 2.3 (2.1, 2.5) |
Pain VAS, mm | ||
 OPAL Broaden | 9.9 (9.4, 10.4) | NA |
 OPAL Beyond | 10.7 (10.1, 11.2) | NA |
HAQ-DI | ||
 OPAL Broaden | 0.2 (0.1, 0.2) | NA |
 OPAL Beyond | 0.2 (0.2, 0.2) | NA |