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Table 3 Magnitude of the contribution of markers of inflammation and disease activity parameters in the HOMA2 indices in the rheumatoid arthritis group

From: Impact of disease activity on impaired glucose metabolism in patients with rheumatoid arthritis

  logHOMA2-IR
R2
logHOMA2-%S
R2
logC-peptide
R2
Base model
 Age, hypertension, BMI, TGL 0.264 0.285 0.201
Base model + inflammation markers
 ESR 0.270 0.293 0.250
 CRP 0.273 0.300 0.209
 IL-6 0.266 0.292 0.196
Base model + RA activity parameters
 MMP3 0.299 0.330 0.199
 DAS28-ESR 0.315 0.336 0.235
 DAS28-CRP 0.321 0.342 0.219
 DAS28-ESR ≥ 5.1 0.355 0.374 0.249
 HAQ 0.308 0.332 0.208
 VAS 0.325 0.343 0.217
 TJC 0.332 0.351 0.211
 SJC 0.280 0.300 0.202
  1. Abbreviations: R2 coefficient of determination, BMI body mass index, CRP C-reactive protein, DAS28 disease activity score of 28 joints, ESR erythrocyte sedimentation rate, HAQ Health Assessment Questionnaire, HOMA2-IR Homeostasis Model Assessment of insulin resistance, HOMA2-%S Homeostasis Model Assessment of insulin sensitivity, IL interleukin, IR insulin resistance, MMP3 matrix metalloproteinase-3, RA rheumatoid arthritis, SJC number of swollen joints, TGL triglycerides, TJC number of tender joints, VAS visual analogue scale (0–100 mm)