|
Dependent variables
|
Independent variables
|
Estimates
|
Std. Error
|
95%CI
|
P value
|
|---|
|
Lower
|
Upper
|
|---|
|
DAS28-ESR
|
Sex (male)
|
−0.58
|
0.14
|
− 0.85
|
− 0.31
|
< 0.0001
|
|
Prednisolone (+)
|
0.48
|
0.12
|
0.23
|
0.72
|
0.0001
|
|
Urinary Na/K ratio
|
0.11
|
0.030
|
0.048
|
0.170
|
0.0004
|
|
Age (1 year)
|
0.0150
|
0.0046
|
0.0055
|
0.024
|
0.0016
|
|
RF (1 IU/mL)
|
0.00054
|
0.00019
|
0.00017
|
0.00091
|
0.0042
|
|
Biological agent (+)
|
−0.23
|
0.098
|
−0.42
|
−0.033
|
0.021
|
|
Anti-CCP antibody (10 U/mL)
|
0.00
|
0.00
|
0.00015
|
0.0048
|
0.037
|
|
BMI
|
−0.024
|
0.014
|
−0.050
|
0.0029
|
0.081
|
|
eGFR (1 ml/min/1.73m2)
|
0.0051
|
0.0030
|
−0.00084
|
0.011
|
0.092
|
|
Smoking (+)
|
−0.18
|
0.19
|
−0.54
|
0.19
|
0.34
|
|
MTX (+)
|
−0.0058
|
0.12
|
−0.23
|
0.22
|
0.96
|
- Results of multiple regression analysis adjusted for urinary Na/K ratio and other variables including sex, age, RF, anti-CCP antibody, smoking status, current therapeutics (the use of Methotrexate, Prednisolone, and biological agents), eGFR, and BMI
- Abbreviations: DAS28-ESR 28-Joint Disease Activity Score using erythrocyte sedimentation rate, RF rheumatoid factor, anti-CCP antibody anti-cyclic citrullinated peptide antibody, BMI Body mass index, eGFR estimated glomerular filtration, MTX methotrexate, CI confidence interval
