Fig. 4
From: Efficacy and safety of sprifermin injection for knee osteoarthritis treatment: a meta-analysis
Effectiveness for sprifermin versus placebo in cartilage thickness improvement. Forest plots of standardized mean difference (SMD) with 95% confidence interval (CI) in total cartilage thickness and cartilage thickness in femorotibial subregional (MFTC, LFTC, cMT, cLT, cMF, cLF) between patients undergoing sprifermin injection and placebo injection. (The three or four effect sizes for each trial in the figure represent the different dose of sprifermin treatment in the same trials)