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Table 1 Demographic and clinical features of the patients

From: Clinical features and relapse risks of IgG4-related ophthalmic disease: a single-center experience in China

Characteristics IgG4-RD IgG4-ROD nIgG4-ROD P value
Number of cases, n 434 255 179  
Male to female 1.32:1 0.96:1 2.14:1 < 0.001*
AECC score 33.0 ± 14.2 37.0 ± 12.9 27.2 ± 14.0 < 0.001*
AECC score ≥ 20, n (%) 344(79.3) 228(89.4) 116(64.8) < 0.001*
Age of disease onset (years), mean ± SD 52.9 ± 13.5 51.1 ± 13.2 55.5 ± 13.5 0.001*
Age of disease diagnosis (years), mean ± SD 55.4 ± 12.9 54.4 ± 12.6 56.9 ± 13.4 0.054
History of allergic disease, n (%) 214(49.3) 167(65.5) 47(26.3) < 0.001*
IgG4-RD RI 11.0 ± 6.2 11.4 ± 6.0 10.2 ± 6.3 0.045*
Number of involved organs, median (IQR) 5(3–6) 6(4–7) 3(2–5) < 0.001*
Number of involved organs, n (%)
 1 organ involved 30(6.9) 4(1.6) 26(14.5) < 0.001*
 2 organs involved 52(12.0) 11(4.3) 41(22.9) < 0.001*
 3 organs involved 46(10.6) 20(7.8) 26(14.5) 0.026*
  ≥ 4 organs involved 306(70.5) 220(86.3) 86(48.0) < 0.001*
  1. The P value refers to the comparison between IgG4-ROD and nIgG4-ROD patients. AECC American College of Rheumatology/European League Against Rheumatism classification criteria, IgG4-RD RI IgG4-RD responder index, SD standard deviation, IQR interquartile range. *P < 0.05