Skip to main content
Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

Fig. 2

Fargesin acts as a potent polarizer towards M2 macrophages. a–c Quantitative PCR analysis of iNOS, IL-1β, and IL-6 in LPS-induced Raw264.7 cells treated with or without fargesin. d, e Quantitative PCR analysis of CD206, and IL-10 in IL-4-stimulated Raw264.7 cells treated with or without fargesin. f After ASC plasmid transfection and treatment with or without fargesin in LPS-induced Raw264.7 cells, the release of IL-1β still needed ATP-induced inflammasome, and then cell supernatants were detected by ELISA. h, g ELISA results for IL-6 and IL-10 levels in Raw264.7 cell supernatant treated with LPS or IL-4 and co-treated with or without fargesin (n = 3). ASC, apoptosis-associated speck

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us