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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats

Fig. 3

Representative micro-CT image of L6 vertebra (a). Compared to the Sham group, the trabeculae were sparser and the width of the canal between trabeculae was higher in the OVX and OVX+PLF groups; a large area of bone trabeculae was missing in the OVX+PLF group. The parameters of L6 trabecular bone (bf). The results of L6 vertebral BMD, bone volume (BV)/total volume (TV), trabecular number (Tb.N; mm-1), trabecular thickness (Tb.Th; μm), and trabecular separation (Tb.Sp; μm) in different groups. Note: *P < 0.05, **P < 0.01; scale bars = 2 mm as indicated

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