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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner

Fig. 2

All CCR6+ memTh subpopulations are detected in RA PBMC and synovial fluid. a Percentage of Th17, Th17.1, DP, and DN cells in 32 treatment-naïve early RA patients. b Representative flow cytometric plot of CCR6+ memTh subpopulations in paired PBMC and SFMC from an established RA patient. c Gene transcription levels after 3 days of culture upon stimulation of anti-CD3 and anti-CD28 as measured by RT-PCR, representing n = 5–10 treatment-naïve early RA patients (mean ± SEM). **p < 0.01, ***p < 0.001, ****p < 0.0001

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