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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort

Fig. 1

Cumulative skin fibrosis worsening, FVC (%pred) worsening, and all-cause mortality events during the course of the study. a Clinically significant worsening of skin fibrosis was defined as an absolute increase of mRSS ≥ 5 units or ≥ 25% as compared to baseline mRSS. b Significant functional progression of ILD was defined as an absolute FVC decline of ≥ 10% as compared to baseline FVC. c Patients’ vital status was confirmed from medical records or death certificates. mRSS modified Rodnan skin score, FVC forced vital capacity. Gray area corresponds to the 95% confidence interval

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