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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: The expansion of activated naive DNA autoreactive B cells and its association with disease activity in systemic lupus erythematosus patients

Fig. 5

Correlation of aNAV B cells with clinical parameters. Correlation between the frequencies of aNAV B cells and clinical parameters in SLE patients (n = 20). a modified SLEDAI-2 K score (left panel), modified SLEDAI-2 K score in patients with an expansion of aNAV B cells (middle panel), and frequencies of aNAV B cells in inactive and active SLE patients (right panel), b ESR, c anti-dsDNA autoantibodies, d C3, and e C4 levels. Spearman’s correlation coefficient (r) was used as metric to calculate correlations between numerical data. Bars represent median with interquartile range. p values were determined by the Mann-Whitney U test: *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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