Fig. 4

Oxylipin profile is different in PsA patients by enthesis involvement. A PLS-DA scores plot of PsA patients with enthesitis (N = 11) versus PsA patients without enthesitis (N = 8). The explained variances for each component are shown in brackets. B Important features identified by PLS-DA. The colored boxes on the right indicate the relative concentrations of the corresponding metabolite in each group under study. C Heatmap performed using the important features identified by PLS-DA which shows different patterns in the 2 groups. D Precursor assignment for the oxylipins that are decreased (blue rectangle) in PsA patients with enthesitis compared to the group without enthesitis; the oxylipins that are increased in PsA patients with enthesitis compared to the group without enthesitis are indicated by a red rectangle