Table 2 Odds ratios for the risk of rheumatoid arthritis by categories of overall tea consumption, overall, stratified by sex, ACPA, and smoking status, and among coffee drinkers among 2237 cases and 4661 controls diagnosed with RA during 2005–2018 in Sweden

Overall

 Number

955/1941

453/847

388/845

441/1028

 OR crude*

0.89 (0.77–1.03)

Ref

0.84 (0.71–1.00)

0.78 (0.66–0.92)

 OR adjusted^±

0.82 (0.70–0.95)

Ref

0.87 (0.73–1.04)

0.85 (0.71–1.01)

Female

 Number

582/1255

358/643

288/622

359/817

 OR crude

0.82 (0.70–0.97)

Ref

0.82 (0.68–1.00)

0.79 (0.65–0.95)

 OR adjusted

0.74 (0.62–0.88)

Ref

0.86 (0.70–1.05)

0.86 (0.70–1.04)

Male

 Number

373/686

95/204

100/223

82/211

 OR crude

1.09 (0.82–1.46)

Ref

0.92 (0.65–1.31)

0.76 (0.52–1.10)

 OR adjusted

1.04 (0.77–1.41)

Ref

0.95 (0.66–1.37)

0.79 (0.54–1.18)

ACPA positive

 Number

637/1156

321/527

268/501

277/630

 OR crude

0.90 (0.76–1.07)

Ref

0.87 (0.71–1.07)

0.71 (0.58–0.87)

 OR adjusted

0.81 (0.67–0.97)

Ref

0.88 (0.71–1.09)

0.76 (0.62–0.94)

ACPA negative

 Number

312/571

129/221

119/251

162/288

 OR crude

0.91 (0.70–1.19)

Ref

0.80 (0.58–1.09)

0.97 (0.72–1.31)

 OR adjusted

0.87 (0.66–1.14)

Ref

0.87 (0.63–1.19)

1.07 (0.78–1.46)

Never smokers

 Number

290/859

164/436

142/433

213/563

 OR crude

0.91 (0.73–1.15)

Ref

0.90 (0.69–1.17)

1.03 (0.81–1.32)

 OR adjusted

0.90 (0.71–1.13)

Ref

0.89 (0.68–1.16)

1.05 (0.82–1.35)

Current smokers

 Number

296/371

89/96

59/78

59/99

 OR crude

0.84 (0.60–1.18)

Ref

0.84 (0.54–1.33)

0.63 (0.40–0.98)

 OR adjusted

0.82 (0.58–1.16)

Ref

0.82 (0.51–1.30)

0.60 (0.38–0.95)

Coffee drinkers

 Number

885/1769

409/768

345/762

341/759

 OR crude

0.93 (0.80–1.08)

Ref

0.84 (0.70–1.00)

0.83 (0.70–0.99)

 OR adjusted

0.86 (0.74–1.00)

Ref

0.86 (0.72–1.03)

0.88 (0.74–1.06)