Fig. 3

Synovial fluid concentrations of A TNF-α, B IL-1β, C CCL2, D CCL3, E CCL5, and F CCL11 were measured using a multiplex assay (n = 20 healthy and n = 54 OA joints). TNF-α was increased in OA joints, and CCL11 was decreased in OA joints. CCL2 and CCL5 did not differ between healthy and OA joints. ns, not significant; *P < 0.05, **P < 0.01. Data are displayed as box-and-whisker plots representing the first and third quartiles, median, and spread of concentrations for healthy and OA samples