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Table 2 Descriptive statistics for %∆CDAI, ACR-N, and ∆HAQ-DI at month 12

From: Differences and similarities in clinical and functional responses among patients receiving tofacitinib monotherapy, tofacitinib plus methotrexate, and adalimumab plus methotrexate: a post hoc analysis of data from ORAL Strategy

 

CDAI

ACR-N

HAQ-DI

Na

Baseline,

mean (SE)

%∆ at month 12,

mean (SE)

Na

At month 12,

mean (SE)

Na

Baseline,

mean (SE)

∆ at month 12,

mean (SE)

Tofacitinib monotherapy

319

38.7 (0.7)

 − 65.3 (1.8)

320

32.2 (6.0)

320

1.59 (0.04)

 − 0.63 (0.04)

Tofacitinib + MTX

309

40.5 (0.7)

 − 74.0 (1.2)

310

49.1 (2.1)

311

1.57 (0.04)

 − 0.67 (0.04)

ADA + MTX

312

38.3 (0.8)

 − 72.2 (1.4)

314

45.1 (2.8)

313

1.55 (0.04)

 − 0.67 (0.03)

  1. ∆, change from baseline; ACR-N, American College of Rheumatology response rate, where ACR is the percentage improvement from baseline in American College of Rheumatology components, and N represents the minimum percentage achieved by each patient; ADA, adalimumab; CDAI, Clinical Disease Activity Index; HAQ-DI, Health Assessment Questionnaire-Disability Index; MTX, methotrexate; SE, standard error
  2. aNumber of patients with month 12 data for ≥ 1 efficacy endpoint