Fig. 3From: Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational loadCross-reactivity of monoclonal AMPA-IgM in germline configuration. Heatmap of a PTM-peptide ELISA with 10 μg/ml mAb and its germline variants (coated 10 μg/ml antigen). A 2D5 B 1G8 C 1E3. All experiments were replicated 2–3 times with similar outcomes. Binding is represented by the optical density at 415 nmBack to article page