Table 1 Descriptive statistics of biomarkers
New serum biomarker measurements | |||
|---|---|---|---|
Biomarker | Description | Median (ng/mL) | Range (ng/mL) |
Serum hsCRP | Acute-phase inflammatory marker | 2093.50 | 281.34–17,914 |
Serum CRPM | Degradation product of CRP | 7.57 | 4.13–15.48 |
Serum C1M | Degradation product of type I collagen | 33.65 | 14.79–58.08 |
Serum C3M | Degradation product of type III collagen | 11.33 | 9.21–20.61 |
Serum CD163ʌ | Inflammatory marker of macrophages | 601.70 | 178.40–1080.50 |
Plasma CD14ʌ | Inflammatory marker of macrophages | 1.89 | 0.98–3.14 |
Plasma CRP* | Acute-phase inflammatory marker | 575.00 | 53.80–6930.00 |
Plasma MMP-3* | Common MMP | 7.63 | 3.70–68.00 |
Plasma MMP-9* | MMP that cleaves type I and type III collagen | 12.60 | ND–30.00 |
Plasma TIMP-1* | Inhibitor of MMP-3 | 36.10 | 24.00–54.00 |
Plasma MMP-3:TIMP-1 | Ratio of MMP-3 to TIMP-1 | 0.24 | 0.13–1.1 |
SF MMP-3* | Common MMP | 308 | 95.50–19,515.00 |
SF MMP-9* | MMP that cleaves type I and type III collagen | 27.30 | 17.00–56.00 |
SF Neutrophil Elastase* | Neutrophil-associated protease | 6842.00 | 1750.60–1,119,905.00 |
SF CD14^ | Inflammatory marker of macrophages | 809.30 | 178.80–1897.00 |
SF CD163^ | Inflammatory marker of macrophages | 845.00 | 267.50–1858.3.00 |