Table 1 ICRS grades of index and control knees of the subjects analyzed in TPX-100-1 and TPX-100-5 studies, respectively at baseline. ICRS grade in each knee was determined as the maximum degree of cartilage defect observed in tibiofemoral knee compartment. Subjects were screened clinically and with MRI, with inclusion criteria applied for patellofemoral OA severity (grades 2–3) only, and agnostic for OA severity in other joint compartments. One control knee failed ICRS grade measurement

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA