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Table 1 Average consumption of rapamycin and metformin. Using the concentration of rapamycin and metformin from the diet analysis, the average doses were calculated for each group in mg of drug per kg body weight per day (mg/kg/day). N = 7–8 per group. Data are presented as mean ± SD

From: Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis


Experimental Diet



Rapamycin consumed (mg/kg/day)

0.72 ± 0.09

0.68 ± 0.08

Metformin consumed (mg/kg/day)


45 ± 5.6