Skip to main content

Table 1 Influence of baseline BMI on RA disease activity, pain and fatigue over 12 months

From: Baseline predictors of remission, pain and fatigue in rheumatoid arthritis: the TITRATE trial

  

Crude

Adjusteda

β (95%CI)

p value

β (95%CI)

p value

Average scores (0, 6 and 12 months)

 DAS28-ESR

Normal

Reference

 

Reference

 

Overweight

0.15 (-0.07,0.38)

0.181

0.08 (-0.15,0.31)

0.506

Obese

0.38 (0.14,0.61)

0.002

0.29 (0.05,0.53)

0.017

 Pain

Normal

Reference

 

Reference

 

Overweight

6.00 (0.86,11.13)

0.022

5.17 (0.29,10.05)

0.038

Obese

8.48 (3.36,13.60)

0.001

8.16 (3.12,13.21)

0.002

 Fatigue

Normal

Reference

 

Reference

 

Overweight

3.59 (-2.61,9.79)

0.256

3.36 (-2.05,8.77)

0.224

Obese

7.96 (1.86,14.05)

0.010

5.66 (0.02,11.30)

0.049

12-month outcomes

  

Crude

Odds ratio (95%CI)

p value

Adjusteda

Odds ratio (95%CI)

p value

 Remission DAS28-ESR (<2.6)

Normal

Reference

 

Reference

 

Overweight

0.95 (0.52, 1.70)

0.853

0.97 (0.50, 1.87)

0.925

Obese

0.32 (0.15, 0.67)

0.002

0.33 (0.16, 0.72)

0.005

 Change in Pain (≥10 units)

Normal

Reference

 

Reference

 

Overweight

1.00 (0.58, 1.72)

0.996

1.11 (0.62, 2.00)

0.719

Obese

0.74 (0.42, 1.29)

0.287

0.68 (0.37, 1.24)

0.213

 Change in Fatigue (≥10 units)

Normal

Reference

 

Reference

 

Overweight

0.69 (0.40, 1.18)

0.172

0.76 (0.42, 1.37)

0.362

Obese

0.53 (0.30, 0.94)

0.029

0.53 (0.29, 0.98)

0.043

  1. aAdjustment for age, gender, ethnicity, disease duration, NHS region and trial arm; BMI: normal n=102, overweight n=105, obese n=92
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us