Table 1 List of significant eQTL associations detected by the various statistical methods in classical and non-classical monocytes at <ā0.1 FDR
Gene (SNP rsID) | Associated transcript | Method | Monocyte subset |
|---|---|---|---|
ITGAM (rs1143679) | TLR7 | Logistic | Classical |
ITGAM (rs1143683) | JAK1 | Logistic | Classical |
TNFAIP3 (rs2230926) | IRF8 | Proportion | Classical |
SPP1 (rs9138) | ARG1 | Logistic | Classical |
SPP1 (rs9138) | IRF1 | Logistic | Classical |
SPP1 (rs9138) | IRF4 | Logistic | Classical |
IRF5 (rs10488631) | IRF1 | Logistic | Non-classical |
IRF7 (rs1061502) | IRF1 | Logistic | Non-classical |
ITGAM (rs1143679) | ARG1 | Gaussian | Non-classical |
ITGAM (rs1143679) | TCF4 | Logistic | Non-classical |
ITGAM (rs1143683) | IL1B | Gaussian | Non-classical |
ITGAM (rs1143683) | TNFA | Gaussian | Non-classical |
TNFAIP3 (rs2230926) | CD274 | Logistic | Non-classical |
TNFAIP3 (rs2230926) | FCER1G | Proportion | Non-classical |
TNFAIP3 (rs2230926) | IL7R | Proportion | Non-classical |
TNFAIP3 (rs2230926) | STAT1 | Proportion | Non-classical |
TNFAIP3 (rs2230926) | STAT2 | Tweedie | Non-classical |
TNFAIP3 (rs2230926) | TNFA | Logistic | Non-classical |
TNFAIP3 (rs2230926) | TYK2 | Proportion | Non-classical |
PTPN22 (rs2476601) | IL5 | Logistic | Non-classical |
SPP1 (rs9138) | IFIT5 | Proportion | Non-classical |
SPP1 (rs9138) | IL1A | Proportion | Non-classical |
SPP1 (rs9138) | IRF1 | Logistic | Non-classical |
SPP1 (rs9138) | TLR3 | Proportion | Non-classical |
SPP1 (rs9138) | TYK2 | Proportion | Non-classical |