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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis

Fig. 1

The expression profiles of CCL20 and CCR6 in SSc patients and healthy controls. The expression of CCL20 and CCR6 was evaluated by immunohistochemistry in the skin sections from diffuse cutaneous SSc (dcSSc) patients, limited cutaneous SSc (lcSSc) patients, and healthy controls (HC). Representative results are shown. Lower panels of each picture exhibit dermal fibroblasts (pointed out with arrowheads) in CCL20 staining and dermal small vessels and inflammatory cells (pointed out with unbroken arrows and dashed arrows, respectively) in CCR6 staining, which are shown with dashed solid squares in upper panels. Horseradish peroxidase activity was detected by 3, 3′-diaminobenzidine. Counterstaining was carried out with methyl green. A scale bar is 100 μm

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