Fig. 2

Expression of GSDMD, IL-1β, and IL-18 was increased in the articular cartilage from mice subjected to MLI and human PTOA patients. qPCR analysis of the gene expression in the articular cartilage from mice (sham surgery or MLI (A)) and human patients (control, OA, or PTOA (B, C)). The dot points reflect different patients or mouse samples. Data are mean ± SD. Student’s t test; *p < 0.05; **p < 0.01; ****p < 0.0001