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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes

Fig. 3

GSDMD was expressed in mouse joint tissues and synovium of human OA patients. AF Representative images of specimens of Gsdmd+/+ mice stained with GSDMD antibody. B, C, E, F Magnified views of the boxed areas in A and D. GI Representative images of specimens of Gsdmd−/− mice stained with GSDMD antibody. Brown and dark red show specific staining. Scale bar = 250 μm (AI). AC, articular cartilage; BM, bone marrow; M, meniscus. J Immunoblotting analysis of GSDMD expression and cleavage in the synovium from 1 normal and 8 OA patients. GAPDH was used as a loading control

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