Table 1 Significantly altered serum metabolites related to humidity in DBA/1 mice
Day 21 - HT vs. CT | Day 42 - HT vs. MT | Day 56 - HT vs. MT | |||||||
|---|---|---|---|---|---|---|---|---|---|
VIP | P value | Trend | VIP | P value | Trend | VIP | P value | Trend | |
Xylitol | 1.40 | 0.004 | ↑ | 1.87 | 0.043 | ↑ | 1.21 | 0.000 | ↑ |
L-aspartic acid | 1.04 | >0.05 | — | <1.0 | >0.05 | — | 1.36 | 0.000 | ↑ |
Dodecanoic acid | 1.09 | 0.007 | ↑ | 1.10 | 0.019 | ↓ | <1.0 | 0.007 | — |
Pyroglutamic acid | 1.10 | 0.014 | ↑ | 1.70 | 0.038 | ↑ | 1.11 | 0.002 | ↑ |
Sucrose | 2.86 | 0.034 | ↓ | <1.0 | >0.05 | — | <1.0 | >0.05 | — |
L-tryptophan | 2.07 | >0.05 | — | <1.0 | >0.05 | — | <1.0 | 0.008 | — |
Ethanolamine | 1.33 | >0.05 | — | <1.0 | >0.05 | — | <1.0 | >0.05 | — |
Triethylene glycol | 1.11 | >0.05 | — | <1.0 | >0.05 | — | <1.0 | >0.05 | — |
L-threonine | 1.37 | >0.05 | — | 2.27 | 0.015 | ↑ | <1.0 | >0.05 | — |
Galactonic acid | 1.31 | >0.05 | — | <1.0 | >0.05 | — | <1.0 | >0.05 | — |
L-valine | <1.0 | >0.05 | — | 1.52 | >0.05 | — | 1.20 | 0.001 | ↓ |
Methyl galactoside | <1.0 | 0.011 | — | 1.39 | >0.05 | — | 1.36 | 0.000 | ↑ |
L-isoleucine | <1.0 | >0.05 | — | 1.20 | >0.05 | — | <1.0 | >0.05 | — |
Glucose oxime | <1.0 | 0.013 | — | 1.49 | >0.05 | — | 1.17 | 0.001 | ↑ |
L-alanine | <1.0 | >0.05 | — | 1.07 | >0.05 | — | 1.01 | 0.023 | ↓ |
Malic acid | <1.0 | >0.05 | — | 1.24 | 0.017 | ↓ | <1.0 | >0.05 | — |
D-gluconic acid | <1.0 | 0.023 | — | 1.31 | 0.007 | ↓ | 1.16 | 0.000 | ↑ |
D-mannose | <1.0 | >0.05 | — | 1.15 | >0.05 | — | 1.27 | 0.000 | ↑ |
Methyltrifluoroacetamide | <1.0 | 0.039 | — | <1.0 | >0.05 | — | 1.28 | 0.000 | ↑ |
Octadecanoic acid | <1.0 | >0.05 | — | <1.0 | >0.05 | — | 1.31 | 0.000 | ↑ |
Campesterol | <1.0 | 0.033 | — | <1.0 | >0.05 | — | 1.25 | 0.000 | ↑ |
1-monopalmitin | <1.0 | 0.022 | — | <1.0 | >0.05 | — | 1.26 | 0.000 | ↑ |
Glycerol monostearate | <1.0 | >0.05 | — | <1.0 | >0.05 | — | 1.23 | 0.000 | ↑ |
Pyridine | <1.0 | 0.034 | — | <1.0 | >0.05 | — | 1.25 | 0.000 | ↓ |