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Table 3 Cox regression was used to analyse the correlation between baseline measurements and the survival of AOSD patients

From: Clinical phenotypes and prognostic factors of adult-onset Still’s disease: data from a large inpatient cohort

 

Univariate analysis

Multivariate analysis

Variables

Hazard ratio (95% CI)

p

Hazard ratio (95% CI)

p

Age at onset, years (continuous)

1.03 (1.00–1.06)

0.026

  

Age at onset, years (categorical)

 <50

0.31 (0.13–0.73)

0.008

  

 ≥50

3.20 (1.36–7.53)

0.008

6.78 (2.10–21.89)

0.001

Gender

 Male

1.32 (0.51–3.36)

0.567

  

 Female

0.76 (0.30–1.95)

0.567

  

Fever ≥ 39 °C

-

0.997

  

Rash

0.59 (0.22–1.59)

0.292

  

Arthralgia

0.66 (0.27–1.61)

0.358

  

ILD

2.92 (1.22–6.98)

0.016

0.52 (0.13–2.14)

0.369

Pharyngalgia

1.29 (0.52–3.17)

0.581

  

Myalgia

1.41 (0.55–3.59)

0.478

  

Pericarditis

3.76 (1.23–11.4)

0.020

1.17 (0.36–3.78)

0.792

Pleurisy

3.04 (1.27–7.26)

0.012

2.17 (0.59–8.03)

0.246

Hepatomegaly

4.14 (1.50–11.38)

0.006

5.05 (1.44–17.70)

0.011

Splenomegaly

1.49 (0.62–3.55)

0.371

  

Lymphadenopathy

1.16 (0.50–2.68)

0.734

  

Ferritin > 1500 ng/mL

2.04 (0.69–6.01)

0.198

  

Infection

12.56 (5.39–29.28)

4.52e−09

15.56 (5.88–41.20)

3.29e−08

MAS

11.88 (4.51–31.30)

5.58e−07

26.82 (7.52–95.60)

3.95e−07

  1. ILD Interstitial lung disease, MAS Macrophage activation syndrome