Table 3 Characteristics of pSS patients with positive and negative SGUS results
Negative (SGUS < 4) | Positive (SGUS ≥ 4) | p | |
|---|---|---|---|
N (%) | 56 (22.8) | 190 (77.2) | - |
Age (S.D.), years | 53.16 (12.99) | 53.16 (11.91) | 0.92 |
Female/male | 54/2 | 185/5 | 0.71 |
Symptom duration, median (range), years | 2 (0.1–27) | 5 (0.1–31) | < 0.001 |
Parotid swelling | 9 (16.1) | 66 (34.7) | 0.008 |
Dental loss | 11 (19.6) | 84 (44.2) | 0.001 |
ANA ≥1:320 | 25 (48.1) | 105 (61.8) | 0.08 |
Anti-SSA positivity | 33 (66.0) | 143 (82.7) | 0.011 |
Anti-SSB positivity | 12 (24.0) | 77 (44.3) | 0.01 |
Positive RF | 29 (58) | 130 (81.8) | 0.001 |
IgG, g/l | 17.1 (6.6) | 21.37 (8.34) | 0.001 |
γ-globulin,% | 21.74 (6.84) | 25.62 (6.47) | 0.01 |
C3, median (range), g/l | 1.15 (0.88–1.49) | 0.96 (0.64–1.66) | 0.07 |
C4, median (range), g/l | 0.18 (0.12–0.38) | 0.17 (0.12–0.34) | 0.951 |
Systemic complications | |||
Cutaneous vasculitis | 6 (10.7) | 25 (13.2) | 0.628 |
Interstitial lung disease | 14 (25) | 50 (26.3) | 0.844 |
Renal involvement | 3 (5.4) | 20 (10.5) | 0.243 |
Nervous system involvement | 3 (5.4) | 10 (5.3) | 0.978 |
Leukopaenia | 14 (25) | 59 (31.1) | 0.384 |
Cryoglobulinaemia | 0 | 1 (0.5)a | 0.586 |