Table 1 Clinical features of SLE patients with/without hematological malignancies
Parameter | Group A (n=15) | Group B (n=57) | P value |
|---|---|---|---|
Female (n, %) | 12 (80.0) | 49 (86.0) | 0.867 |
Age at SLE diagnosis (years), M (Q1–Q3) | 52 (42–63) | 31 (25–47) | 0.002* |
Age at HM diagnosis (years, mean ± SD) | 52±15 | - | - |
Lymphadenopathy (n, %) | 9 (60.0) | 26 (45.6) | 0.321 |
Fever (n, %) | 9 (60.0) | 21 (36.8) | 0.106 |
Infection (n, %) | 9 (60.0) | 13 (22.8) | 0.014* |
Hypertension (n, %) | 1 (6.7) | 9 (15.8) | 0.625 |
Diabetes mellitus (n, %) | 0 (0) | 1 (1.8) | 1.000 |
Dyslipidemia (n,%) | 13 (13/14, 92.9) | 40 (40/56, 71.4) | 0.186 |
Smoking (n, %) | 1 (6.7) | 5 (8.8) | 1.000 |
Alcohol consumption (n, %) | 1 (6.7) | 2 (3.5) | 1.000 |
Family history of tumor (n, %) | 2 (13.3) | 4 (7.0) | 0.793 |
Rash (n, %) | 4 (26.7) | 20 (35.1) | 0.538 |
Arthralgia (n, %) | 5 (33.3) | 14 (24.6) | 0.721 |
Pleural effusion (n, %) | 5 (33.3) | 15 (26.3) | 0.829 |
Pericardial effusion (n, %) | 5 (33.3) | 16 (29.1) | 0.936 |
Splenomegaly (n, %) | 7 (46.7) | 9 (15.8) | 0.027* |