Skip to main content
Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Characterization and use of the ECV304 autoantigenic citrullinome to understand anti-citrullinated protein/peptide autoantibodies in rheumatoid arthritis

Fig. 4

ECV304 ELISA for detection of autoantibodies in RA. A ROC curve, AUC of 0.716 (p < 0.001) and Youden index cut-off of 0.044, provided a sensitivity of 50% and specificity of 95.2%. B ECV304 ELISA scatterplot of non-RA (n = 84) and RA (n = 177) samples. The number (%) and titers (OD units as mean ± SE) of EVC304 positive sera were higher in RA with (48.6% positive and 0.163 ± 0.021 OD versus non-RA with 7.1% positive and 0.018 ± 0.004 OD (p < 0.0001 unpaired T test)

Back to article page