Table 3 “Non-criteria” clinical manifestations present in the seronegative antiphospholipid syndrome group
Clinical manifestation | |
|---|---|
Non-obstetric (n, %) | n = 82 |
Migraine | 23 (28.0) |
Brain MRI white matter lesions | 21 (25.6) |
Superficial vein thrombosis | 19 (23.2) |
Thrombocytopenia | 17 (20.7) |
Livedo reticularis | 10 (12.2) |
Valvular heart disease | 8 (9.8) |
Raynaud’s phenomenon | 6 (7.3) |
Seizures | 6 (7.3) |
Coombs’ positivity | 5 (6.1) |
Memory lapses | 5 (6.1) |
Transverse myelitis | 3 (3.7) |
Hemolytic anemia | 3 (3.7) |
Cognitive dysfunction | 3 (3.7) |
Pseudo-multiple sclerosis | 3 (3.7) |
Cardiac microvascular disease | 3 (3.7) |
Skin ulcers | 2 (2.4) |
APS nephropathy | 2 (2.4) |
Livedoid vasculopathy | 1 (1.2) |
Obstetric | n = 66 |
Two spontaneous abortions <10 weeks | 11 (16.7) |
Late IUGR (>34 weeks) | 5 (7.6) |
Infertility | 4 (6.1) |
Premature birth between 34 and 37 weeks | 3 (4.5) |
Placental abruption | 3 (4.5) |
≥ 2 or more IVF failures | 2 (3.0) |
Puerperal preeclampsia | 1 (1.5) |
Late preeclampsia (>34 weeks) | 1 (1.5) |
Placental hematoma | 1 (1.5) |
Puerperal Thrombosis | 1 (1.5) |