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Table 1 General characteristics of anti-CCP+ low (> 1 to < 3x ULN) and high level (> 3x ULN) individuals (SD = standard deviation)

From: Prioritising referrals of individuals at-risk of RA: guidance based on results of a 10-year national primary care observational study

  Overall anti-CCP+ (n = 151) Anti-CCP+ low level (n = 53) Anti-CCP+ high level (n = 98) P value
Sex, female n (%) 93 (61.6) 38 (71.7) 55 (56.1) 0.060
Mean age (SD; range) in years 52 (15.2; 19–83) 46 (15.3; 18–77) 55 (14.2; 25–83) 0.001
Mean follow-up (SD; range) in weeks 105 (121.8; 2–560) 133 (117.2; 6–527) 91 (122.1; 2–560) 0.041
Family history of RA, n (%) 76 (53.1) 28 (57.1) 48 (51.1) 0.489
Smoking status, n (%) Never 53 (37.1)
Ever smoked 90 (62.9)
Never 20 (40.0)
Ever smoked 30 (60.0)
Never 33 (35.5)
Ever smoked 60 (64.5)
0.590
• Never
n (%)
53 (37.1) 20 (40.0) 33 (35.5)  
• Previous
n (%)
65 (45.5) 21 (42.0) 44 (47.3)
• Current
n (%)
25 (17.5) 9 (18.0) 16 (17.2)
Progression to IA, n (%) 68 (45%) 7 (13%) 61 (62%) < 0.001